Anti-RREB1 antibody,Abcam,AB64168

Target data Transcription factor that binds specifically to the RAS-responsive elements (RRE) of gene promoters (PubMed : 12700664). Represses the angiotensinogen gene (By similarity). Negatively regulates the transcriptional activity of AR (By similarity). Potentiates the transcriptional activity of NEUROD1 (By similarity). Binds specifically to the allelic variant of the CDKN2A promoter present in Balb/c mice, which leads to a down-regulation of CDKN2A expression in this strain, and, as a consequence, to an elevated susceptibility to pristane-induced tumors (PubMed : 12700664). Promotes brown adipocyte differentiation (PubMed : 27923061). May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression (By similarity). See full target information Ras-responsive element-binding protein 1