Anti-RUNX2 antibody [EPR22858-106] - ChIP Grade,Abcam,AB236639
What is this antibody validated in? Anti-RUNX2 antibody [EPR22858-106] - ChIP Grade (ab236639) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), ChIP in Human, Mouse, Rat samples. What is the molecular weight of RUNX2? Anti-RUNX2 [EPR22858-106] - ChIP Grade (ab236639) specifically detects a band for RUNX2 (UniProt: Q13950) at a molecular weight of 57kDa. Trusted by the scientific community Anti-RUNX2 [EPR22858-106] - ChIP Grade (ab236639) was first used in a scientific publication in 2019 and has been cited over 60 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EPR22858-106] also available for your convenience: ab236639, Carrier free - ab264077 , Carrier free - ab275219 , PE - ab318316 , APC - ab318419 , Alexa Fluor® 488 - ab318522 , Alexa Fluor® 647 - ab318625 , Alexa Fluor® 594 - ab318728 , Alexa Fluor® 555 - ab318828 , Alexa Fluor® 750 - ab321481 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
ChIC/CUT&RUN-seq, IP, WB, IHC-P, ChIP
Platform ID
BAB274478745

Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis (PubMed : 28505335, PubMed : 28703881, PubMed : 28738062). Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. In osteoblasts, supports transcription activation : synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity). Inhibits KAT6B-dependent transcriptional activation. See full target information RUNX2
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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