Anti-Rad21 antibody [EPR22506-15] - ChIP Grade,Abcam,AB217678

What is this antibody validated in? Anti-Rad21 antibody [EPR22506-15] - ChIP Grade (ab217678) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF), ChIP in Human, Mouse, Rat samples. What is the molecular weight of Rad21? Anti-Rad21 [EPR22506-15] - ChIP Grade (ab217678) specifically detects a band for Rad21 (UniProt: O60216) at a molecular weight of 72kDa. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EPR22506-15] also available for your convenience: ab217678, Carrier free - ab254483 , APC - ab305774 , HRP - ab305775 , Alkaline Phosphatase - ab308643 , Alexa Fluor® 488 - ab309618 , Alexa Fluor® 647 - ab309984 , Alexa Fluor® 594 - ab310345 , Alexa Fluor® 555 - ab311867 , Alexa Fluor® 568 - ab312336 , Alexa Fluor® 750 - ab321393 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

Flow Cyt (Intra), IP, ChIP, ICC/IF, IHC-P, WB, ChIC/CUT&RUN-seq

Platform ID

BAB076240152

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Rad21 antibody [EPR22506-15] - ChIP Grade
Cat. No.AB217678
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationFlow Cyt (Intra), IP, ChIP, ICC/IF, IHC-P, WB, ChIC/CUT&RUN-seq
ClonalityMonoclonal
Clone NumberEPR22506-15
Concentration0.518 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Double-strand-break repair protein rad21 homolog. As a member of the cohesin complex, involved in sister chromatid cohesion from the time of DNA replication in S phase to their segregation in mitosis, a function that is essential for proper chromosome segregation, post-replicative DNA repair, and the prevention of inappropriate recombination between repetitive regions (PubMed : 11509732). The cohesin complex may also play a role in spindle pole assembly during mitosis (PubMed : 11590136). In interphase, cohesins may function in the control of gene expression by binding to numerous sites within the genome (By similarity). May control RUNX1 gene expression (Probable). Binds to and represses APOB gene promoter (PubMed : 25575569). May play a role in embryonic gut development, possibly through the regulation of enteric neuron development (By similarity).. 64-kDa C-terminal product. May promote apoptosis. See full target information RAD21

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