Anti-Rad51 antibody,Abcam,AB63801
What is this antibody validated in? Anti-Rad51 antibody (ab63801) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Xenopus laevis samples. What is the molecular weight of Rad51? Anti-Rad51 (ab63801) specifically detects a band for Rad51 (UniProt: Q06609) at a molecular weight of 37kDa. Trusted by the scientific community Anti-Rad51 (ab63801) was first used in a scientific publication in 2008 and has been cited over 130 times in peer-reviewed journals. Reviewed by scientists Anti-Rad51 (ab63801) has over 5 independent reviews from customers.
Host
Rabbit
Reactivity
Human, Xenopus laevis
Application
ICC/IF, WB
Platform ID
BAB451327610
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR) (PubMed : 12205100, PubMed : 18417535, PubMed : 20231364, PubMed : 20348101, PubMed : 22325354, PubMed : 23509288, PubMed : 23754376, PubMed : 26681308, PubMed : 28575658, PubMed : 32640219). Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange (PubMed : 12205100, PubMed : 18417535, PubMed : 15226506, PubMed : 20231364, PubMed : 20348101, PubMed : 23509288, PubMed : 23754376, PubMed : 26681308, PubMed : 28575658). Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template (PubMed : 12205100, PubMed : 18417535, PubMed : 20231364, PubMed : 20348101, PubMed : 23509288, PubMed : 23754376, PubMed : 26681308, PubMed : 28575658, PubMed : 38459011). Recruited to resolve stalled replication forks during replication stress (PubMed : 27797818, PubMed : 31844045). Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR (PubMed : 12442171, PubMed : 24141787). Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3 (PubMed : 20413593). Also involved in interstrand cross-link repair (PubMed : 26253028). See full target information RAD51
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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