Anti-Ras antibody [4F3],Abcam,AB55391

This product was changed from ascites to tissue culture supernatant on 13 th Feb 2019. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.

Host

Mouse

Reactivity

Human

Application

WB, Flow Cyt

Platform ID

BAB390245679

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Ras antibody [4F3]
Cat. No.AB55391
HostMouse
IsotypeIgG2a
ReactivityHuman
ApplicationWB, Flow Cyt
ClonalityMonoclonal
Clone Number4F3
ImmunogenRecombinant Fragment Protein within Human KRAS aa 1-150. The exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data The protein expressed by the KRAS gene binds GDP/GTP and has intrinsic GTPase activity. It plays an important role in regulating cell proliferation and may contribute to oncogenic events by inducing transcriptional silencing of tumor suppressor genes in colorectal cancer cells through a ZNF304-dependent mechanism. This supplementary information is collated from multiple sources and compiled automatically. See full target information KRAS

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