Anti-Respiratory Syncytial Virus G Glycoprotein antibody [RSV133],Abcam,AB94966

What is this antibody validated in? Anti-Respiratory Syncytial Virus G Glycoprotein antibody [RSV133] (ab94966) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-Fr), Immunocytochemistry/immunofluorescence (ICC/IF), ELISA in Respiratory syncytial virus samples. What is the molecular weight of Respiratory Syncytial Virus G Glycoprotein? Anti-Respiratory Syncytial Virus G Glycoprotein [RSV133] (ab94966) specifically detects a band for Respiratory Syncytial Virus G Glycoprotein (UniProt: P03423) at a molecular weight of 33kDa.

Host

Mouse

Reactivity

Respiratory syncytial virus

Application

IHC-Fr, WB, ICC/IF, ELISA

Platform ID

BAB643069323

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Respiratory Syncytial Virus G Glycoprotein antibody [RSV133]
Cat. No.AB94966
HostMouse
IsotypeIgG1
ReactivityRespiratory syncytial virus
ApplicationIHC-Fr, WB, ICC/IF, ELISA
ClonalityMonoclonal
Clone NumberRSV133
Concentration1 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.02% Sodium azide Constituents: 99.98% PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Isoform Membrane-bound glycoprotein G. Attaches the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection (PubMed : 10400758, PubMed : 10864656, PubMed : 3655746). Interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection (PubMed : 11477410, PubMed : 26107373, PubMed : 26658574). Unlike the other paramyxovirus attachment proteins, lacks both neuraminidase and hemagglutinating activities (Probable).. Isoform Secreted glycoprotein G. Helps the virus escape antibody-dependent restriction of replication by acting as an antigen decoy and by modulating the activity of leukocytes bearing Fc-gamma receptors. See full target information G

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