Anti-Respiratory Syncytial Virus M2-1 Protein antibody [EPR28649-58],Abcam,AB323319

Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Human respiratory syncytial virus A (strain A2)

Application

I-ELISA, ICC/IF, WB, IHC-P

Platform ID

BAB955575570

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Respiratory Syncytial Virus M2-1 Protein antibody [EPR28649-58]
Cat. No.AB323319
HostRabbit
IsotypeIgG
ReactivityHuman respiratory syncytial virus A (strain A2)
ApplicationI-ELISA, ICC/IF, WB, IHC-P
ClonalityMonoclonal
Clone NumberEPR28649-58
Concentration0.506 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Acts as a tetrameric transcription processivity factor that binds in a competitive manner to RNA and the phosphoprotein (P) to prevent premature termination during transcription (PubMed : 19386701, PubMed : 22675274). Transcription anti-terminator that enhances readthrough of intergenic junctions during viral transcription (PubMed : 10364337, PubMed : 27194388, PubMed : 8552680, PubMed : 9420254). Preferentially binds to poly(A)-rich sequences (PubMed : 24434552). Plays a role in the association of the matrix protein with the nucleocapsid, which initiates assembly and budding (PubMed : 18579594). Also, can activate host NF-kappa-B through association with host RELA (PubMed : 15629770). See full target information M2-1

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