Anti-Respiratory Syncytial Virus M2-1 Protein antibody [RSV5H5],Abcam,AB94805

What is this antibody validated in? Anti-Respiratory Syncytial Virus M2-1 Protein antibody [RSV5H5] (ab94805) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP), Immunocytochemistry/immunofluorescence (ICC/IF), ELISA in Respiratory syncytial virus samples. Trusted by the scientific community Anti-Respiratory Syncytial Virus M2-1 Protein [RSV5H5] (ab94805) was first used in a scientific publication in 2010 and has been cited over 10 times in peer-reviewed journals.

Host

Mouse

Reactivity

Respiratory syncytial virus

Application

ELISA, ICC/IF, IP, WB

Platform ID

BAB268081817

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Respiratory Syncytial Virus M2-1 Protein antibody [RSV5H5]
Cat. No.AB94805
HostMouse
IsotypeIgG1
ReactivityRespiratory syncytial virus
ApplicationELISA, ICC/IF, IP, WB
ClonalityMonoclonal
Clone NumberRSV5H5
Concentration1 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.02% Sodium azide Constituents: 99.98% PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Acts as a tetrameric transcription processivity factor that binds in a competitive manner to RNA and the phosphoprotein (P) to prevent premature termination during transcription (PubMed : 19386701, PubMed : 22675274). Transcription anti-terminator that enhances readthrough of intergenic junctions during viral transcription (PubMed : 10364337, PubMed : 27194388, PubMed : 8552680, PubMed : 9420254). Preferentially binds to poly(A)-rich sequences (PubMed : 24434552). Plays a role in the association of the matrix protein with the nucleocapsid, which initiates assembly and budding (PubMed : 18579594). Also, can activate host NF-kappa-B through association with host RELA (PubMed : 15629770). See full target information M2-1

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