Anti-Respiratory Syncytial Virus Nucleoprotein antibody [B023],Abcam,AB22501

Target data Encapsidates the viral RNA genome by forming a left-handed helical nucleocapsid that protects the RNA from nucleases (PubMed : 19965480, PubMed : 23677789, PubMed : 31229488). RNA replication depends on the availability of soluble nucleoprotein (PubMed : 22623798, PubMed : 9299631). The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication (PubMed : 22623798). Together with the phosphoprotein, sequesters host NF-kappa-B in inclusion bodies (IBs) thereby inhibiting this host defense pathway (PubMed : 32878896). May also act as a modulator of the innate immune response by sequestration of host IFIH1/MDA5 and MAVS into IBs (PubMed : 22623778). See full target information N