Anti-Respiratory Syncytial Virus Nucleoprotein antibody [RSV1C3],Abcam,AB94806

What is this antibody validated in? Anti-Respiratory Syncytial Virus Nucleoprotein antibody [RSV1C3] (ab94806) is a mouse monoclonal antibody and is validated for use in Immunoprecipitation (IP), Immunocytochemistry/immunofluorescence (ICC/IF), ELISA in Respiratory syncytial virus samples. Trusted by the scientific community Anti-Respiratory Syncytial Virus Nucleoprotein [RSV1C3] (ab94806) was first used in a scientific publication in 2010 and has been cited over 10 times in peer-reviewed journals.

Host

Mouse

Reactivity

Respiratory syncytial virus

Application

ELISA, ICC/IF, IP

Platform ID

BAB830613052

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Respiratory Syncytial Virus Nucleoprotein antibody [RSV1C3]
Cat. No.AB94806
HostMouse
IsotypeIgG2a
ReactivityRespiratory syncytial virus
ApplicationELISA, ICC/IF, IP
ClonalityMonoclonal
Clone NumberRSV1C3
Concentration1 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.02% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Encapsidates the viral RNA genome by forming a left-handed helical nucleocapsid that protects the RNA from nucleases (PubMed : 19965480, PubMed : 23677789, PubMed : 31229488). RNA replication depends on the availability of soluble nucleoprotein (PubMed : 22623798, PubMed : 9299631). The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication (PubMed : 22623798). Together with the phosphoprotein, sequesters host NF-kappa-B in inclusion bodies (IBs) thereby inhibiting this host defense pathway (PubMed : 32878896). May also act as a modulator of the innate immune response by sequestration of host IFIH1/MDA5 and MAVS into IBs (PubMed : 22623778). See full target information N

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