Anti-Respiratory Syncytial Virus Phosphoprotein antibody [RSVH102],Abcam,AB94965
Fusion partner: PS-NS/1-Ag4
Host
Mouse
Reactivity
Respiratory syncytial virus
Application
IP, WB, IHC-Fr, ICC/IF, ELISA
Platform ID
BAB143119299

Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Plays critical roles in regulating RNA replication and transcription through its interactions with multiple proteins (PubMed : 25568210, PubMed : 26474524). Tethers the RNA-directed RNA polymerase L to the nucleoprotein-RNA complex (PubMed : 26474524). Recruits the M2-1 protein, a processivity factor that is required for efficient transcription of viral RNA (PubMed : 26474524). Acts as a chaperone for neo-synthesized nucleoprotein by forming an N-P complex that preserves N in a monomeric and RNA-free state and prevents the association of nascent N with host cell RNAs (PubMed : 25568210). Recruits the host phosphatase PP1 to inclusion bodies to regulate viral transcription (PubMed : 29489893). Together with the nucleoprotein, sequesters host NF-kappa-B in inclusion bodies (IBs) thereby inhibiting this host defense pathway (By similarity). See full target information P
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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