Anti-Respiratory Syncytial Virus Subgroup A G Glycoprotein antibody [RSV1C2],Abcam,AB94967
Myeloma: PS-NS/1-Ag4 ab94967 is useful for the identification and location of subgroup A Respiratory Syncytial Virus G glycoprotein expression. This antibody confers passive protection against HRSV subgroup A in an animal model of Human Respiratory Syncytial Virus infection. Recommended growth conditions: Growth medium RPMI with 25mM Hepes, 2mM additional glutamine and 10% heat inactivated foetal calf serum
Host
Mouse
Reactivity
Respiratory syncytial virus
Application
ICC/IF, WB, IHC-Fr, ELISA
Platform ID
BAB455625546
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Isoform Membrane-bound glycoprotein G. Attaches the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection (PubMed : 10400758, PubMed : 10864656, PubMed : 3655746). Interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection (PubMed : 11477410, PubMed : 26107373, PubMed : 26658574). Unlike the other paramyxovirus attachment proteins, lacks both neuraminidase and hemagglutinating activities (Probable).. Isoform Secreted glycoprotein G. Helps the virus escape antibody-dependent restriction of replication by acting as an antigen decoy and by modulating the activity of leukocytes bearing Fc-gamma receptors. See full target information G
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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