Anti-Respiratory Syncytial virus type A G protein antibody [HL2354],Abcam,AB317208

Host

Rabbit

Reactivity

Human respiratory syncytial virus A

Application

WB

Platform ID

BAB768131793

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Respiratory Syncytial virus type A G protein antibody [HL2354]
Cat. No.AB317208
HostRabbit
IsotypeIgG
ReactivityHuman respiratory syncytial virus A
ApplicationWB
ClonalityMonoclonal
Clone NumberHL2354
ImmunogenRecombinant Fragment Protein within Human respiratory syncytial virus A (strain A2) G.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Isoform Membrane-bound glycoprotein G. Attaches the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection (PubMed : 10400758, PubMed : 10864656, PubMed : 3655746). Interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection (PubMed : 11477410, PubMed : 26107373, PubMed : 26658574). Unlike the other paramyxovirus attachment proteins, lacks both neuraminidase and hemagglutinating activities (Probable).. Isoform Secreted glycoprotein G. Helps the virus escape antibody-dependent restriction of replication by acting as an antigen decoy and by modulating the activity of leukocytes bearing Fc-gamma receptors. See full target information G

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