Anti-Rhodopsin antibody [1D4],Abcam,AB5417

Product Specifications Anti-Rhodopsin antibody [1D4] (ab5417) is a mouse monoclonal antibody and is validated for use in ELISA, ICC/IF, IHC-FoFr, IHC-Fr, IHC-P, IP, WB in amphibian, cow, human, mouse, rat, zebrafish samples. Anti-Rhodopsin antibody [1D4] (ab5417) specifically detects Rhodopsin (UniProt ID: P08100; Molecular weight: 39kDa) and is sold in 100 µL selling sizes. Quality and Validation Abcam's high quality validation processes ensure Anti-Rhodopsin antibody [1D4] (ab5417) has high sensitivity and specificity. Anti-Rhodopsin antibody [1D4] (ab5417) has been cited over 108 times in peer reviewed journals and is trusted by the scientific community. Anti-Rhodopsin antibody [1D4] (ab5417) has 4 independent reviews from customers.

Host

Mouse

Reactivity

Mouse, Human, Amphibian, Cow, Zebrafish, Rat

Application

WB, IHC-FoFr, IP, ICC/IF, IHC-P, IHC-Fr, ELISA

Platform ID

BAB019356205

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Rhodopsin antibody [1D4]
Cat. No.AB5417
HostMouse
IsotypeIgG1
ReactivityMouse, Human, Amphibian, Cow, Zebrafish, Rat
ApplicationWB, IHC-FoFr, IP, ICC/IF, IHC-P, IHC-Fr, ELISA
ClonalityMonoclonal
Clone Number1D4
Concentration1 mg/mL Batch dependent concentration
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide Constituents: PBS, 0.1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Photoreceptor required for image-forming vision at low light intensity (PubMed : 7846071, PubMed : 8107847). Required for photoreceptor cell viability after birth (PubMed : 12566452, PubMed : 2215617). Light-induced isomerization of the chromophore 11-cis-retinal to all-trans-retinal triggers a conformational change that activates signaling via G-proteins (PubMed : 26200343, PubMed : 28524165, PubMed : 28753425, PubMed : 8107847). Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (PubMed : 26200343, PubMed : 28524165). See full target information RHO

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