Anti-S100A4 antibody [EPR2761(2)],Abcam,AB124805
What is this antibody validated in? Anti-S100A4 antibody [EPR2761(2)] (ab124805) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human samples. What is the molecular weight of S100A4? Anti-S100A4 [EPR2761(2)] (ab124805) specifically detects a band for S100A4 (UniProt: P26447) at a molecular weight of 12kDa. Trusted by the scientific community Anti-S100A4 [EPR2761(2)] (ab124805) was first used in a scientific publication in 2012 and has been cited over 50 times in peer-reviewed journals. Reviewed by scientists Anti-S100A4 [EPR2761(2)] (ab124805) has over 5 independent reviews from customers. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-S100A4 antibody [EPR2761(2)] (ab124805) has been confirmed by Western blot testing in S100A4 Knockout A549 cell line, ab261865 . Other related products We have a range of other formats of antibody clone [EPR2761(2)] also available for your convenience: ab124805, Alexa Fluor® 647 - ab196168 , Alexa Fluor® 488 - ab196380 , Carrier free - ab216003 , Carrier free - ab281227 , PE - ab305390 , APC - ab305391 , HRP - ab305392 , Alkaline Phosphatase - ab309072 , Alexa Fluor® 594 - ab310689 , Alexa Fluor® 555 - ab312219 , Alexa Fluor® 568 - ab312708 , Alexa Fluor® 750 - ab320979 Species reactivity Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Human
Application
ICC/IF, IHC-P, Flow Cyt (Intra), IP, WB
Platform ID
BAB087634680
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Calcium-binding protein that plays a role in various cellular processes including motility, angiogenesis, cell differentiation, apoptosis, and autophagy (PubMed : 16707441, PubMed : 23752197, PubMed : 30713770). Increases cell motility and invasiveness by interacting with non-muscle myosin heavy chain (NMMHC) IIA/MYH9 (PubMed : 16707441). Mechanistically, promotes filament depolymerization and increases the amount of soluble myosin-IIA, resulting in the formation of stable protrusions facilitating chemotaxis (By similarity). Also modulates the pro-apoptotic function of TP53 by binding to its C-terminal transactivation domain within the nucleus and reducing its protein levels (PubMed : 23752197). Within the extracellular space, stimulates cytokine production including granulocyte colony-stimulating factor and CCL24 from T-lymphocytes (By similarity). In addition, stimulates T-lymphocyte chemotaxis by acting as a chemoattractant complex with PGLYRP1 that promotes lymphocyte migration via CCR5 and CXCR3 receptors (PubMed : 26654597, PubMed : 30713770). See full target information S100A4
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
- Products>Trial Size Antibodies
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