Anti-SAP30L antibody - C-terminal,Abcam,AB220491

Target data Isoform 1. Functions as a transcription repressor, probably via its interaction with histone deacetylase complexes (PubMed : 16820529, PubMed : 18070604). Involved in the functional recruitment of the class 1 Sin3-histone deacetylase complex (HDAC) to the nucleolus (PubMed : 16820529). Binds DNA, apparently without sequence-specificity, and bends bound double-stranded DNA (PubMed : 19015240). Binds phosphoinositol phosphates (phosphoinositol 3-phosphate, phosphoinositol 4-phosphate and phosphoinositol 5-phosphate) via the same basic sequence motif that mediates DNA binding and nuclear import (PubMed : 19015240, PubMed : 26609676).. Isoform 2. Functions as a transcription repressor; isoform 2 has lower transcription repressor activity than isoform 1 and isoform 3.. Isoform 3. Functions as a transcription repressor; its activity is marginally lower than that of isoform 1. See full target information SAP30L