Anti-SARS-CoV-2 nucleocapsid protein antibody,Abcam,AB273167
This product is manufactured by BioVision, an Abcam company and was previously called A2061 Anti-SARS-CoV-2 Antibody. A2061-50 is the same size as the 50 μg size of ab273167.
Applications overview
Tick: Tested and Guaranteed to work X: Will not work —: No data
Host
Rabbit
Reactivity
SARS-CoV-2
Application
WB
Platform ID
BAB339458804
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M (PubMed : 33264373). Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Attenuates the stress granules formation by reducing host G3BP1 access to host mRNAs under stress conditions (PubMed : 34901782, PubMed : 36534661).. May block host chemokine function in vivo, facilitating viral replication and transmission (PubMed : 35921414). Acts by being secreted into the extracellular space where it competes to host chemokines for binding to host glycosaminoglycans (GAG) (PubMed : 35921414).. May induce inflammasome responses in cultured cells and mice. Acts by interacting with host NLRP3 to facilitate inflammasome assembly, which induces cytokine release that may play a role in COVID lung injury. See full target information N
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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