Anti-SATB2 antibody,Abcam,AB34735
What is this antibody validated in? Anti-SATB2 antibody (ab34735) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB) in Mouse samples. What is the molecular weight of SATB2? Anti-SATB2 (ab34735) specifically detects a band for SATB2 (UniProt: Q9UPW6) at a molecular weight of 83kDa. Trusted by the scientific community Anti-SATB2 (ab34735) was first used in a scientific publication in 2007 and has been cited over 90 times in peer-reviewed journals.
Host
Rabbit
Reactivity
Mouse
Application
WB
Platform ID
BAB402839631
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Required for the initiation of the upper-layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes, probably by modulating Bcl11b expression. Repressor of Ctip2 and regulatory determinant of corticocortical connections in the developing cerebral cortex. May play an important role in palate formation. Acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation. See full target information Satb2
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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