Anti-SATB2 antibody [EPNCIR130A],Abcam,AB92446
This antibody was developed as part of a collaboration between Epitomics, the National Cancer Institute's Center for Cancer Research and the lab of John Niederhuber. View antibodies from NCI Center for Cancer Research Collaboration . Product Specifications Anti-SATB2 antibody [EPNCIR130A] (ab92446) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-P, WB in human, mouse, rat samples. Anti-SATB2 antibody [EPNCIR130A] (ab92446) specifically detects SATB2 (UniProt ID: Q9UPW6; Molecular weight: 83kDa) and is sold in 100 µL and 1 mL selling sizes. Quality and Validation Abcam's high quality manufacturing and validation processes ensure Anti-SATB2 antibody [EPNCIR130A] (ab92446) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-SATB2 antibody [EPNCIR130A] (ab92446) has been confirmed by testing in knockout samples. Anti-SATB2 antibody [EPNCIR130A] (ab92446) has been cited over 73 times in peer reviewed journals and is trusted by the scientific community. Anti-SATB2 antibody [EPNCIR130A] (ab92446) has 8 independent reviews from customers. Related Products Antibody clone EPNCIR130A is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 647, Alexa Fluor® 594, APC, PE ( ab196536 , ab207040 , ab225051 , ab225052 ). Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
Flow Cyt (Intra), IHC-P, WB, ICC/IF
Platform ID
BAB027852125
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Required for the initiation of the upper-layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes, probably by modulating BCL11B expression. Repressor of Ctip2 and regulatory determinant of corticocortical connections in the developing cerebral cortex. May play an important role in palate formation. Acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation. See full target information SATB2
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