Anti-SCARA5 antibody,Abcam,AB76720

Host

Rabbit

Reactivity

Mouse

Application

IHC-Fr, WB

Platform ID

BAB028151981

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-SCARA5 antibody
Cat. No.AB76720
HostRabbit
IsotypeIgG
ReactivityMouse
ApplicationIHC-Fr, WB
ClonalityPolyclonal
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationConstituents: Whole serum
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Preferentially binds ferritin light chain (FTL) compared to heavy chain (FTH1). See full target information Scara5

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