Anti-SCD1 antibody [EPR21963],Abcam,AB236868

What is this antibody validated in? Anti-SCD1 antibody [EPR21963] (ab236868) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of SCD1? Anti-SCD1 [EPR21963] (ab236868) specifically detects a band for SCD1 (UniProt: O00767) at a molecular weight of 42kDa. Trusted by the scientific community Anti-SCD1 [EPR21963] (ab236868) was first used in a scientific publication in 2018 and has been cited over 20 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-SCD1 antibody [EPR21963] (ab236868) has been confirmed by Western blot testing in SCD Knockout HeLa cell line, ab265220 . Other related products We have a range of other formats of antibody clone [EPR21963] also available for your convenience: ab236868, Carrier free - ab238171 , Alexa Fluor® 647 - ab314925 , Alexa Fluor® 488 - ab315182 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

IHC-P, WB, Flow Cyt (Intra), IP, ICC/IF

Platform ID

BAB965770674

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-SCD1 antibody [EPR21963]
Cat. No.AB236868
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationIHC-P, WB, Flow Cyt (Intra), IP, ICC/IF
ClonalityMonoclonal
Clone NumberEPR21963
Concentration0.606 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates (PubMed : 15907797, PubMed : 18765284). Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (PubMed : 15907797, PubMed : 18765284). Gives rise to a mixture of 16 : 1 and 18 : 1 unsaturated fatty acids (PubMed : 15610069). Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation (By similarity). Plays an important role in body energy homeostasis (By similarity). Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (By similarity). See full target information SCD

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