Anti-SDHB antibody [EPR13042(B)],Abcam,AB178423

What is this antibody validated in? Anti-SDHB antibody [EPR13042(B)] (ab178423) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunohistochemistry (IHC-P) in Human samples. What is the molecular weight of SDHB? Anti-SDHB [EPR13042(B)] (ab178423) specifically detects a band for SDHB (UniProt: P21912) at a molecular weight of 32kDa. Trusted by the scientific community Anti-SDHB [EPR13042(B)] (ab178423) was first used in a scientific publication in 2013 and has been cited over 10 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-SDHB antibody [EPR13042(B)] (ab178423) has been confirmed by Western blot testing in SDHB Knockout HEK-293 cells. Other related products We have a range of other formats of antibody clone [EPR13042(B)] also available for your convenience: ab178423, Carrier free - ab250046 , PE - ab305931 , APC - ab305932 , HRP - ab305933 , Alkaline Phosphatase - ab308925 , Alexa Fluor® 488 - ab309855 , Alexa Fluor® 647 - ab310223 , Alexa Fluor® 594 - ab310670 , Alexa Fluor® 555 - ab312201 , Alexa Fluor® 568 - ab312689 , Alexa Fluor® 750 - ab321213 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Human

Application

WB, Flow Cyt (Intra), IHC-P, IP

Platform ID

BAB591682736

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-SDHB antibody [EPR13042(B)]
Cat. No.AB178423
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationWB, Flow Cyt (Intra), IHC-P, IP
ClonalityMonoclonal
Clone NumberEPR13042(B)
Concentration0.087 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Iron-sulfur protein (IP) subunit of the succinate dehydrogenase complex (mitochondrial respiratory chain complex II), responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (PubMed : 26925370, PubMed : 27604842). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate (By similarity). Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate (By similarity). See full target information SDHB

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