Anti-SDHB antibody [HL2251],Abcam,AB317178

Host

Rabbit

Reactivity

Human, Dog

Application

WB, IHC-P

Platform ID

BAB216695230

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-SDHB antibody [HL2251]
Cat. No.AB317178
HostRabbit
IsotypeIgG
ReactivityHuman, Dog
ApplicationWB, IHC-P
ClonalityMonoclonal
Clone NumberHL2251
ImmunogenRecombinant Fragment Protein within Human SDHB.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Iron-sulfur protein (IP) subunit of the succinate dehydrogenase complex (mitochondrial respiratory chain complex II), responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (PubMed : 26925370, PubMed : 27604842). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate (By similarity). Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate (By similarity). See full target information SDHB

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