Anti-SELK antibody,Abcam,AB139949

Target data Required for Ca(2+) flux in immune cells and plays a role in T-cell proliferation and in T-cell and neutrophil migration (PubMed : 21220695). Involved in endoplasmic reticulum-associated degradation (ERAD) of soluble glycosylated proteins (By similarity). Required for palmitoylation and cell surface expression of CD36 and involved in macrophage uptake of low-density lipoprotein and in foam cell formation (PubMed : 23444136). Together with ZDHHC6, required for palmitoylation of ITPR1 in immune cells, leading to regulate ITPR1 stability and function (PubMed : 25368151). Plays a role in protection of cells from ER stress-induced apoptosis (By similarity). Protects cells from oxidative stress when overexpressed in cardiomyocytes (By similarity). See full target information Selenok