Anti-SEMA6A antibody [HL2120],Abcam,AB317139

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB

Platform ID

BAB279976105

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-SEMA6A antibody [HL2120]
Cat. No.AB317139
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ApplicationWB
ClonalityMonoclonal
Clone NumberHL2120
ImmunogenRecombinant Fragment Protein within Human SEMA6A.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Cell surface receptor for PLXNA2 that plays an important role in cell-cell signaling. Required for normal granule cell migration in the developing cerebellum. Promotes reorganization of the actin cytoskeleton and plays an important role in axon guidance in the developing central nervous system. Can act as repulsive axon guidance cue. Has repulsive action towards migrating granular neurons. May play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation.. (Microbial infection) Acts as a receptor for P.sordellii toxin TcsL in the in the vascular endothelium. See full target information SEMA6A

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