Anti-SERCA1 ATPase antibody [VE121G9],Abcam,AB2819

This product was switched from a hybridoma to a recombinant production format on 25th October 2021. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Mouse

Reactivity

Mouse, Human

Application

WB, IHC-Fr, IHC-P

Platform ID

BAB780625793

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-SERCA1 ATPase antibody [VE121G9]
Cat. No.AB2819
HostMouse
IsotypeIgG1
ReactivityMouse, Human
ApplicationWB, IHC-Fr, IHC-P
ClonalityMonoclonal
Clone NumberVE121G9
Concentration1.023 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Key regulator of striated muscle performance by acting as the major Ca(2+) ATPase responsible for the reuptake of cytosolic Ca(2+) into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen (PubMed : 10914677, PubMed : 11438520, PubMed : 15189864, PubMed : 18075584, PubMed : 23996003, PubMed : 24270570, PubMed : 29081402). Contributes to calcium sequestration involved in muscular excitation/contraction. See full target information ATP2A1

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