Anti-SESN3 antibody,Abcam,AB97792

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

WB, ICC/IF

Platform ID

BAB593881680

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-SESN3 antibody
Cat. No.AB97792
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationWB, ICC/IF
ClonalityPolyclonal
Concentration1.36 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human SESN3 aa 1-300. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 10% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway (PubMed : 25263562). May also regulate the insulin-receptor signaling pathway through activation of TORC2 (By similarity). This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses (By similarity). May prevent the accumulation of reactive oxygen species (ROS) through the alkylhydroperoxide reductase activity born by the N-terminal domain of the protein (By similarity). See full target information SESN3

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