Anti-SH3BP5 antibody,Abcam,AB126231
Host
Rabbit
Reactivity
Human
Application
WB
Platform ID
BAB407437423
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-SH3BP5 antibody
Cat. No.AB126231
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationWB
ClonalityPolyclonal
Concentration0.65 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human SH3BP5 aa 1-250. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Functions as a guanine nucleotide exchange factor (GEF) with specificity for RAB11A and RAB25 (PubMed : 26506309, PubMed : 30217979). Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death. See full target information SH3BP5
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
Request a product
Please provide the required information below so that we can quickly source your products.