Anti-SHANK1 antibody,Abcam,AB154224

Host

Rabbit

Reactivity

Mouse, Human

Application

WB, IHC-Fr, IHC-P

Platform ID

BAB657562363

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-SHANK1 antibody
Cat. No.AB154224
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationWB, IHC-Fr, IHC-P
ClonalityPolyclonal
Concentration0.53 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human SHANK1 aa 2100 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 10% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction. See full target information SHANK1

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