Anti-SIGLEC8 antibody [7C9],Abcam,AB103398

Host

Mouse

Reactivity

Human

Application

ELISA

Platform ID

BAB721143094

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-SIGLEC8 antibody [7C9]
Cat. No.AB103398
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationELISA
ClonalityMonoclonal
Clone Number7C9
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human SIGLEC8. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A/G
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.02% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Putative adhesion molecule that mediates sialic-acid dependent binding to blood cells (PubMed : 10625619, PubMed : 10856141). Preferentially binds to alpha-2,3-linked sialic acid. Also binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface (PubMed : 10625619). Recognizes simultaneously epitopes having a terminal N-acetylneuraminic acid (sialic acid) and an underlying 6-O-sulfated galactose. Preferentially binds to Gal-6-sulfated sialyl-Lewis X glycan epitopes (PubMed : 27357658). See full target information SIGLEC8

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