Anti-SIK3 antibody,Abcam,AB254568
Host
Chicken
Reactivity
Rat
Application
ICC/IF, WB
Platform ID
BAB971268034
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
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Product Specifications
Scientific Background
Specifications
NameAnti-SIK3 antibody
Cat. No.AB254568
HostChicken
IsotypeIgY
ReactivityRat
ApplicationICC/IF, WB
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human SIK3 aa 1150-1250. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Positive regulator of mTOR signaling that functions by triggering the degradation of DEPTOR, an mTOR inhibitor. Involved in the dynamic regulation of mTOR signaling in chondrocyte differentiation during skeletogenesis (PubMed : 30232230). Negatively regulates cAMP signaling pathway possibly by acting on CRTC2/TORC2 and CRTC3/TORC3 (Probable). Prevents HDAC4 translocation to the nucleus (By similarity). See full target information SIK3
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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