Anti-SLC10A2/ASBT antibody,Abcam,AB134837

Host

Goat

Reactivity

Human

Application

IHC-P

Platform ID

BAB284873753

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-SLC10A2/ASBT antibody
Cat. No.AB134837
HostGoat
IsotypeIgG
ReactivityHuman
ApplicationIHC-P
ClonalityPolyclonal
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human SLC10A2 aa 300 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.3 Preservative: 0.02% Sodium azide Constituents: 99% Tris buffered saline, 0.5% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine (PubMed : 7592981, PubMed : 9458785, PubMed : 9856990). Transports various bile acids, unconjugated or conjugated, such as cholate and taurocholate (PubMed : 7592981, PubMed : 9458785, PubMed : 9856990). Also responsible for bile acid transport in the renal proximal tubules, a salvage mechanism that helps conserve bile acids (Probable). Works collaboratively with the Na(+)-taurocholate cotransporting polypeptide (NTCP), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling of bile acids during enterohepatic circulation (PubMed : 33222321). See full target information SLC10A2

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