Anti-SLC12A1/NKCC2 antibody [EPR28176-90],Abcam,AB313640

Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB, IHC-P

Platform ID

BAB784923729

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-SLC12A1/NKCC2 antibody [EPR28176-90]
Cat. No.AB313640
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ApplicationWB, IHC-P
ClonalityMonoclonal
Clone NumberEPR28176-90
Concentration0.545 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Renal sodium, potassium and chloride ion cotransporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation. Electrically silent transporter system.. Isoform A. High affinity, high capacity cotransporter for sodium, potassium and chloride ions, with a coupling ratio 1Na(+) : 1K(+) : 2Cl(-).. Isoform B. High affinity, low capacity cotransporter for sodium, potassium and chloride ions, with a coupling ratio 1Na(+) : 1K(+) : 2Cl(-).. Isoform F. Low affinity, low capacity cotransporter for sodium, potassium and chloride ions, with a coupling ratio 1Na(+) : 1K(+) : 2Cl(-). See full target information Slc12a1

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