Anti-SLC32A1/VGAT antibody [EPR26258-9],Abcam,AB308062

Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

IHC-Fr, IHC-P, ICC/IF

Platform ID

BAB660660875

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-SLC32A1/VGAT antibody [EPR26258-9]
Cat. No.AB308062
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ApplicationIHC-Fr, IHC-P, ICC/IF
ClonalityMonoclonal
Clone NumberEPR26258-9
Concentration0.527 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Antiporter that exchanges vesicular protons for cytosolic 4-aminobutanoate or to a lesser extend glycine, thus allowing their secretion from nerve terminals (PubMed : 16701208, PubMed : 26912364, PubMed : 27601664, PubMed : 9395291). The transport is equally dependent on the chemical and electrical components of the proton gradient (PubMed : 27601664, PubMed : 9395291). May also transport beta-alanine (By similarity). Acidification of GABAergic synaptic vesicles is a prerequisite for 4-aminobutanoate uptake (PubMed : 27601664). See full target information Slc32a1

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