Anti-SLC32A1/VGAT antibody [L118/80],Abcam,AB307448

Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected] What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Mouse

Reactivity

Rat, Mouse

Application

IHC-Fr, WB, ICC/IF, IHC-P

Platform ID

BAB285673369

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-SLC32A1/VGAT antibody [L118/80]
Cat. No.AB307448
HostMouse
IsotypeIgG2a
ReactivityRat, Mouse
ApplicationIHC-Fr, WB, ICC/IF, IHC-P
ClonalityMonoclonal
Clone NumberL118/80
Concentration0.988 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Antiporter that exchanges vesicular protons for cytosolic 4-aminobutanoate or to a lesser extend glycine, thus allowing their secretion from nerve terminals (PubMed : 16701208, PubMed : 26912364, PubMed : 27601664, PubMed : 9395291). The transport is equally dependent on the chemical and electrical components of the proton gradient (PubMed : 27601664, PubMed : 9395291). May also transport beta-alanine (By similarity). Acidification of GABAergic synaptic vesicles is a prerequisite for 4-aminobutanoate uptake (PubMed : 27601664). See full target information Slc32a1

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