Anti-SLC5A6 antibody [EPR30529-531],Abcam,AB325124

Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Human

Application

ICC/IF, WB, IHC-P

Platform ID

BAB223591918

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-SLC5A6 antibody [EPR30529-531]
Cat. No.AB325124
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationICC/IF, WB, IHC-P
ClonalityMonoclonal
Clone NumberEPR30529-531
Concentration0.514 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Sodium-dependent multivitamin transporter that mediates the electrogenic transport of pantothenate, biotin, lipoate and iodide (PubMed : 10329687, PubMed : 15561972, PubMed : 19211916, PubMed : 20980265, PubMed : 21570947, PubMed : 22015582, PubMed : 25809983, PubMed : 25971966, PubMed : 27904971, PubMed : 28052864, PubMed : 31754459). Functions as a Na(+)-coupled substrate symporter where the stoichiometry of Na(+) : substrate is 2 : 1, creating an electrochemical Na(+) gradient used as driving force for substrate uptake (PubMed : 10329687, PubMed : 20980265). Required for biotin and pantothenate uptake in the intestine across the brush border membrane (PubMed : 19211916). Plays a role in the maintenance of intestinal mucosa integrity, by providing the gut mucosa with biotin (By similarity). Contributes to the luminal uptake of biotin and pantothenate into the brain across the blood-brain barrier (PubMed : 25809983). See full target information SLC5A6

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