Anti-SMG7 antibody,Abcam,AB126984
Host
Rabbit
Reactivity
Human, Mouse
Application
IHC-P, WB
Platform ID
BAB913084711
Abcam
Contact
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Fax: +44 (0)1223 215 215
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Product Specifications
Scientific Background
Specifications
NameAnti-SMG7 antibody
Cat. No.AB126984
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse
ApplicationIHC-P, WB
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human SMG7 aa 700-1050. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: PBS, 20% Glycerol (glycerin, glycerine), 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Plays a role in nonsense-mediated mRNA decay. Recruits UPF1 to cytoplasmic mRNA decay bodies. Together with SMG5 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation. See full target information SMG7
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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