Anti-SNRP70/U1-70K antibody [EPR28616-89],Abcam,AB316762

Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB, IHC-P

Platform ID

BAB789121713

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-SNRP70/U1-70K antibody [EPR28616-89]
Cat. No.AB316762
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ApplicationWB, IHC-P
ClonalityMonoclonal
Clone NumberEPR28616-89
Concentration0.512 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome (PubMed : 19325628, PubMed : 25555158). SNRNP70 binds to the loop I region of U1-snRNA (PubMed : 19325628, PubMed : 2467746, PubMed : 25555158).. Isoform 3. Truncated isoforms that lack the RRM domain cannot bind U1-snRNA.. Isoform 4. Truncated isoforms that lack the RRM domain cannot bind U1-snRNA. See full target information SNRNP70

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.