Anti-SOX10 antibody [BC34],Abcam,AB195364

Product Specifications Anti-SOX10 antibody [BC34] (ab195364) is a mouse monoclonal antibody and is validated for use in IHC-P in human samples. Anti-SOX10 antibody [BC34] (ab195364) specifically detects SOX10 (UniProt ID: P56693; Molecular weight: 50kDa) and is sold in 100µL selling sizes. Quality and Validation Abcam's high quality validation processes ensure Anti-SOX10 antibody [BC34] (ab195364) has high sensitivity and specificity.

Host

Mouse

Reactivity

Human

Application

IHC-P

Platform ID

BAB602977312

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-SOX10 antibody [BC34]
Cat. No.AB195364
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationIHC-P
ClonalityMonoclonal
Clone NumberBC34
ImmunogenRecombinant Fragment Protein within Human SOX10. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.099% Sodium azide Constituents: 99% Water
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Transcription factor that plays a central role in developing and mature glia (By similarity). Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination (By similarity). Once induced, MYRF cooperates with SOX10 to implement the myelination program (By similarity). Transcriptional activator of MITF, acting synergistically with PAX3 (PubMed : 21965087). Transcriptional activator of MBP, via binding to the gene promoter (By similarity). See full target information SOX10

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