Anti-SOX10 antibody [BLR080G] - BSA free,Abcam,AB272074

ab272074 is the carrier-free version of ab265587 . REACH authorisation Abcam has not and does not intend to apply for the REACH Authorisation of customers' uses of products that contain European Authorisation list (Annex XIV) substances. It is the responsibility of our customers to check the necessity of application of REACH Authorisation, and any other relevant authorisations, for their intended uses. Conjugation ready Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications. Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Host

Rabbit

Reactivity

Human

Application

IP, ICC, IHC-P

Platform ID

BAB227989806

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-SOX10 antibody [BLR080G] - BSA free
Cat. No.AB272074
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIP, ICC, IHC-P
ClonalityMonoclonal
Clone NumberBLR080G
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human SOX10 aa 400 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 8.2 Preservative: 0.09% Sodium azide Constituents: 98% Borate buffered saline
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Transcription factor that plays a central role in developing and mature glia (By similarity). Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination (By similarity). Once induced, MYRF cooperates with SOX10 to implement the myelination program (By similarity). Transcriptional activator of MITF, acting synergistically with PAX3 (PubMed : 21965087). Transcriptional activator of MBP, via binding to the gene promoter (By similarity). See full target information SOX10

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