Anti-SOX10 antibody [EPR4007],Abcam,AB155279

Product Specifications Anti-SOX10 antibody [EPR4007] (ab155279) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-Fr, WB in human, mouse, rat samples. Anti-SOX10 antibody [EPR4007] (ab155279) specifically detects SOX10 (UniProt ID: P56693; Molecular weight: 50kDa) and is sold in 100 µL and 1 mL selling sizes. Quality and Validation Abcam's high quality manufacturing and validation processes ensure Anti-SOX10 antibody [EPR4007] (ab155279) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-SOX10 antibody [EPR4007] (ab155279) has been cited over 93 times in peer reviewed journals and is trusted by the scientific community. Anti-SOX10 antibody [EPR4007] (ab155279) has 7 independent reviews from customers. Related Products Antibody clone EPR4007 is also available pre-conjugated to a variety of labels for your convenience - PE, APC, Alkaline Phosphatase, Alexa Fluor® 488, Alexa Fluor® 647, Alexa Fluor® 594, Alexa Fluor® 555, Alexa Fluor® 568, Alexa Fluor® 750 ( ab305382 , ab305383 , ab309014 , ab309657 , ab310021 , ab310390 , ab311916 , ab312387 , ab321140 ). Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

WB, IHC-Fr, Flow Cyt (Intra), ICC/IF

Platform ID

BAB165508547

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-SOX10 antibody [EPR4007]
Cat. No.AB155279
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationWB, IHC-Fr, Flow Cyt (Intra), ICC/IF
ClonalityMonoclonal
Clone NumberEPR4007
Concentration0.172 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Transcription factor that plays a central role in developing and mature glia (By similarity). Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination (By similarity). Once induced, MYRF cooperates with SOX10 to implement the myelination program (By similarity). Transcriptional activator of MITF, acting synergistically with PAX3 (PubMed : 21965087). Transcriptional activator of MBP, via binding to the gene promoter (By similarity). See full target information SOX10

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