Anti-SOX11 antibody [CL0142],Abcam,AB154138

The antibody solution should be gently mixed before use.

Host

Mouse

Reactivity

Mouse, Human

Application

ICC/IF, IHC-P

Platform ID

BAB853102252

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-SOX11 antibody [CL0142]
Cat. No.AB154138
HostMouse
IsotypeIgG2a
ReactivityMouse, Human
ApplicationICC/IF, IHC-P
ClonalityMonoclonal
Clone NumberCL0142
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human SOX11 aa 50-200. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Transcription factor that acts as a transcriptional activator (PubMed : 24886874, PubMed : 26543203). Binds cooperatively with POU3F2/BRN2 or POU3F1/OCT6 to gene promoters, which enhances transcriptional activation (By similarity). Acts as a transcriptional activator of TEAD2 by binding to its gene promoter and first intron (By similarity). Plays a redundant role with SOX4 and SOX12 in cell survival of developing tissues such as the neural tube, branchial arches and somites, thereby contributing to organogenesis (By similarity). See full target information SOX11

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