Anti-SOX17 antibody [EPR20684],Abcam,AB224637

Product Specifications Anti-SOX17 antibody [EPR20684] (ab224637) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in ICC/IF, IHC-P, IP, WB in human, mouse, rat samples. Anti-SOX17 antibody [EPR20684] (ab224637) specifically detects SOX17 (UniProt ID: Q9H6I2; Molecular weight: 44kDa) and is sold in 100 µL and 1 mL selling sizes. Quality and Validation Abcam's high quality manufacturing and validation processes ensure Anti-SOX17 antibody [EPR20684] (ab224637) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-SOX17 antibody [EPR20684] (ab224637) has been confirmed by testing in knockout samples. Anti-SOX17 antibody [EPR20684] (ab224637) has been cited over 14 times in peer reviewed journals and is trusted by the scientific community. Anti-SOX17 antibody [EPR20684] (ab224637) has 6 independent reviews from customers. Related Products Antibody clone EPR20684 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 647, Alexa Fluor® 594, Alexa Fluor® 568, Alexa Fluor® 555, Alexa Fluor® 750 ( ab311117 , ab311745 , ab313025 , ab313227 , ab321416 ). Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Shipping conditions update: ambient shipping This product will be delivered at ambient temperature instead of chilled – this is by design. Extensive stability testing confirmed that our products are suitable for shipment under ambient conditions and maintain expected quality. Why the change? It’s part of our commitment to more sustainable packaging solutions, with ambient deliveries using eco-friendly materials such as recyclable cardboard instead of polystyrene. What you need to know Ambient shipments come clearly marked on the delivery note. No ice will be included in ambient shipments, but mixed orders (ambient and cold-chain items) will still arrive with ice packs to protect temperature-sensitive products. Warranty coverage remains fully valid, aligned with our validated shipping method. Please store the product as per the datasheet instructions upon receipt. Find out more - https://www.abcam.com/en-us/support/shipping-storage-support/ambient-shipping

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

IHC-P, WB, ICC/IF, IP

Platform ID

BAB915683463

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-SOX17 antibody [EPR20684]
Cat. No.AB224637
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationIHC-P, WB, ICC/IF, IP
ClonalityMonoclonal
Clone NumberEPR20684
Concentration0.738 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingConditional Ambient
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Acts as a transcription regulator that binds target promoter DNA (PubMed : 33952808). Binds to the sequences 5'-AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal development of the definitive gut endoderm. Required for normal looping of the embryonic heart tube. Plays an important role in embryonic and postnatal vascular development, including development of arteries. Plays an important role in postnatal angiogenesis, where it is functionally redundant with SOX18. Required for the generation and maintenance of fetal hematopoietic stem cells, and for fetal hematopoiesis. Probable transcriptional activator in the premeiotic germ cells. See full target information SOX17

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.