Anti-SOX2 antibody [9-9-3],Abcam,AB79351

What is this antibody validated in? Anti-SOX2 antibody [9-9-3] (ab79351) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunocytochemistry/immunofluorescence (ICC/IF) in Apteronotus leptorhynchus, Human, Mouse samples. What is the molecular weight of SOX2? Anti-SOX2 [9-9-3] (ab79351) specifically detects a band for SOX2 (UniProt: P48431) at a molecular weight of 34kDa. Trusted by the scientific community Anti-SOX2 [9-9-3] (ab79351) was first used in a scientific publication in 2010 and has been cited over 100 times in peer-reviewed journals. Reviewed by scientists Anti-SOX2 [9-9-3] (ab79351) has over 15 independent reviews from customers. Other related products We have a range of other formats of antibody clone [9-9-3] also available for your convenience: ab79351, Carrier free - ab264112 Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]

Host

Mouse

Reactivity

Mouse, Human, Apteronotus leptorhynchus

Application

Flow Cyt (Intra), ICC/IF, WB

Platform ID

BAB478214698

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-SOX2 antibody [9-9-3]
Cat. No.AB79351
HostMouse
IsotypeIgG1
ReactivityMouse, Human, Apteronotus leptorhynchus
ApplicationFlow Cyt (Intra), ICC/IF, WB
ClonalityMonoclonal
Clone Number9-9-3
Concentration1 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 6.97% L-Arginine
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Binds to the proximal enhancer region of NANOG (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency (PubMed : 18035408). Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity). May function as a switch in neuronal development (By similarity). See full target information SOX2

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