Anti-SOX2 antibody,Abcam,AB97959

Anti-SOX2 antibody (ab97959) is a rabbit polyclonal antibody and is validated for use in ICC/IF, IHC-P and WB. Anti-SOX2 antibody (ab97959) was first used in a scientific publication in 2009 and has been cited over 736 times in peer reviewed journals. It's performance in Western blot, immunofluorescence and IHC in human, mouse and rat samples is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-SOX2 antibody (ab97959) has high sensitivity and specificity. Anti-SOX2 antibody (ab97959) has 72 independent reviews from customers. Anti-SOX2 antibody (ab97959) specifically detects SOX2 (UniProt ID: P48431; Molecular weight: 35kDa) and is sold in 100 µg selling sizes. SOX2 is a crucial transcription factor in neuro research, particularly for its role in maintaining neural stem cell pluripotency and regulating neural development. It is essential for the proliferation and differentiation of neural progenitor cells, influencing brain development and repair. Researchers use SOX2 to study neural stem cell behaviour, neurogenesis and the mechanisms underlying neurodevelopmental disorders, making it vital for understanding brain development and potential regenerative therapies. Additionally, SOX2 plays a significant role in gliomas, particularly glioblastoma (GBM), the most aggressive form of brain cancer. Elevated SOX2 levels are associated with poor prognosis and tumor progression in glioblastoma patients. Targeting SOX2 expression and function is being explored as a potential therapeutic strategy to combat gliomas and improve patient outcomes.

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

WB, ICC/IF, IHC-P

Platform ID

BAB728239686

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-SOX2 antibody
Cat. No.AB97959
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationWB, ICC/IF, IHC-P
ClonalityPolyclonal
Concentration0.9 - 1 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data The protein expressed by the gene SOX2 is critical for early embryogenesis and for the pluripotency of embryonic stem cells (PubMed : 18035408). This supplementary information is collated from multiple sources and compiled automatically. See full target information SOX2

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