Anti-SOX2 antibody [SP76],Abcam,AB93689

What is this antibody validated in? Anti-SOX2 antibody [SP76] (ab93689) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of SOX2? Anti-SOX2 [SP76] (ab93689) specifically detects a band for SOX2 (UniProt: P48431) at a molecular weight of 34kDa. Collaboration Anti-SOX2 [SP76] (ab93689) is a clone from the portfolio of Spring Bioscience (Roche) SP clones which have been optimised for immunohistochemistry (IHC). Trusted by the scientific community Anti-SOX2 [SP76] (ab93689) was first used in a scientific publication in 2010 and has been cited over 30 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 20µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [SP76] also available for your convenience: ab93689, Carrier free - ab243909 , ab279622, Alexa Fluor® 647 - ab279687 , Alexa Fluor® 488 - ab282185 , PE - ab314247

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

IHC-P, Flow Cyt (Intra), WB, ICC/IF

Platform ID

BAB228289662

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-SOX2 antibody [SP76]
Cat. No.AB93689
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationIHC-P, Flow Cyt (Intra), WB, ICC/IF
ClonalityMonoclonal
Clone NumberSP76
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A/G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.6 Preservative: 0.1% Sodium azide Constituents: PBS, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Binds to the proximal enhancer region of NANOG (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency (PubMed : 18035408). Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity). May function as a switch in neuronal development (By similarity). See full target information SOX2

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