Anti-SPINK1/P12 antibody,Abcam,AB203579

Host

Rabbit

Reactivity

Rat

Application

IHC-P

Platform ID

BAB104426616

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-SPINK1/P12 antibody
Cat. No.AB203579
HostRabbit
IsotypeIgG
ReactivityRat
ApplicationIHC-P
ClonalityPolyclonal
ImmunogenSynthetic Peptide within Rat Serine protease inhibitor Kazal-type 1 aa 50 to C-terminus conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Proclin 300 Constituents: 50% Glycerol (glycerin, glycerine), 48.98% TBS, 1X, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Serine protease inhibitor which exhibits anti-trypsin activity (PubMed : 3202973, PubMed : 3597401). In the pancreas, protects against trypsin-catalyzed premature activation of zymogens (By similarity).. In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production (By similarity). See full target information Serine protease inhibitor Kazal-type 1

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