Anti-ST2 antibody - BSA free,Abcam,AB25877
What is this antibody validated in? Anti-ST2 antibody - BSA free (ab25877) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of ST2? Anti-ST2 - BSA free (ab25877) specifically detects a band for ST2 (UniProt: P14719) at a molecular weight of 40kDa. Trusted by the scientific community Anti-ST2 - BSA free (ab25877) was first used in a scientific publication in 2005 and has been cited over 20 times in peer-reviewed journals.
Host
Rabbit
Reactivity
Mouse, Human, Rat
Application
WB, ICC/IF, IHC-P, IHC (PFA fixed)
Platform ID
BAB606175776
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Receptor for interleukin-33 (IL-33) which plays crucial roles in innate and adaptive immunity, contributing to tissue homeostasis and responses to environmental stresses together with coreceptor IL1RAP (PubMed : 17675517, PubMed : 18450470, PubMed : 22660580, PubMed : 29045903). Its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8 (By similarity). Possibly involved in helper T-cell function (By similarity). Upon tissue injury, induces UCP2-dependent mitochondrial rewiring that attenuates the generation of reactive oxygen species and preserves the integrity of Krebs cycle required for persistent production of itaconate and subsequent GATA3-dependent differentiation of inflammation-resolving alternatively activated macrophages (PubMed : 34644537).. Isoform B. Inhibits IL-33 signaling. See full target information Il1rl1
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
Please provide the required information below so that we can quickly source your products.