Anti-SULT2B1 antibody [007] - BSA and Azide free,Abcam,AB276055

Host

Rabbit

Reactivity

Human

Application

IP, WB

Platform ID

BAB046543149

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-SULT2B1 antibody [007] - BSA and Azide free
Cat. No.AB276055
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIP, WB
ClonalityMonoclonal
Clone Number007
ImmunogenRecombinant Fragment Protein within Human SULT2B1 aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationConstituents: PBS
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation. Responsible for the sulfation of cholesterol (PubMed : 12145317, PubMed : 19589875). Catalyzes sulfation of the 3beta-hydroxyl groups of steroids, such as, pregnenolone and dehydroepiandrosterone (DHEA) (PubMed : 12145317, PubMed : 16855051, PubMed : 21855633, PubMed : 9799594). Preferentially sulfonates cholesterol, while it has also significant activity with pregnenolone and DHEA (PubMed : 12145317, PubMed : 21855633). Plays a role in epidermal cholesterol metabolism and in the regulation of epidermal proliferation and differentiation (PubMed : 28575648).. Isoform 2. Sulfonates pregnenolone but not cholesterol. See full target information SULT2B1

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