Anti-SV2A antibody,Abcam,AB77177

Host

Goat

Reactivity

Rat, Human

Application

WB, ICC

Platform ID

BAB984861506

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-SV2A antibody
Cat. No.AB77177
HostGoat
IsotypeIgG
ReactivityRat, Human
ApplicationWB, ICC
ClonalityPolyclonal
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human SV2A aa 650-700. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.3 Preservative: 0.02% Sodium azide Constituents: 0.5% BSA, 0.5% Tris buffered saline
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity).. (Microbial infection) Receptor for the C.botulinum neurotoxin type A2 (BoNT/A, botA); glycosylation is not essential but enhances the interaction (PubMed : 29649119). Probably also serves as a receptor for the closely related C.botulinum neurotoxin type A1. See full target information SV2A

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